Grapefruit juice, inhibiting the isoenzyme of the intestinal wall of CYP3A4, has a pronounced effect on the metabolism of a number of drugs, which must be taken into account when prescribing drugs whose concentration in the blood plasma requires careful monitoring.
The combination of piperacillin / tazobactam with tigecycline is a safe, well-tolerated and effective treatment option for patients with hematological diseases and neutropenic fever.
An important topic discussed during U.S. Digestive Awareness Week was new strategies for treating viral hepatitis C, including the ability to prescribe regimens without using interferons.
Rifaximin is effective in reducing the incidence of recurrent diarrhea in patients who have previously been treated with traditional medicines active against Clostridium difficile.
The number of reports regarding the isolation of vancomycin-resistant Staphylococcus aureus (VRSA) is significantly higher than the frequency of confirmed cases of resistance to this antibiotic in vitro or an ineffective treatment of vancomycin for staphylococcal infections.
Determining the concentration of procalcitonin and a highly sensitive C-reactive protein in the blood increases the accuracy of the approaches currently used to diagnose community-acquired pneumonia, in addition to clinical symptoms.