According to a large observational study conducted in Norway, the use of nitrofurantoin during pregnancy leads to a slight increase in the risk of birth defects.
The high prevalence of methicillin-resistant Staphylococcus aureus clinical isolates with a high BMC value of vancomycin requires an aggressive empirical dosage of the drug to reach target concentrations of more than 15 μg / ml.
In the United States for the period from 2001 to 2011 there is a clear trend to reduce the frequency of pediatrician visits for acute otitis media, especially after the introduction of the 13-valent pneumococcal conjugate vaccine.
Therapy to eradicate H. pylori in patients with functional dyspepsia resistant to conventional therapy and diagnosed with H. pylori infection is no more effective than a simple course of antacid drugs.
The introduction of ceftazidime in patients with severe intra-abdominal infections by continuous intravenous administration is more preferable than its appointment in intermittent mode.
Daptomycin is effective against infections of the skin and soft tissues caused by strains of Staphylococcus aureus sensitive to methicillin and resistant to methicillin.